ABSTRACT
Objective To analyze the clinical characteristics and risk factors of multiple drug -resistant bacteria infection in patients with diabetic foot .Methods The clinical data of 60 patients with diabetic foot were retrospectively analyzed , including diabetic foot infected ( positive group ) and uninfected multiple drug -resistant bacteria(negative group),30 cases in each group.Application of SPSS 17.0 statistical software for infection and clinical characteristics of the single factor analysis , through the Logistics regression analyzed the risk factors of infection . Results A total of 130 strains bacteria were isolated in the positive group ,of which more than 64 strains of drug-resistant bacteria,the detection rate was 49.23％;The top three for staphylococcus aureus (60.00％),enterobacter (53.33％) and verdigris pseudomonas (31.57％).Single factor analysis results showed that age , hypertension between the two groups had no statistically significant differences (all P>0.05);Positive group in the use of antibiotics prior to admission time,ulcerated area,etc.,compared with the negative group the differences were statistically significant (t=1.812, -7.268,all P <0.05).Multiple factors analysis showed that admission ,antibiotics,ulcerated area, osteomyelitis were risk factors of positive infection in patients .Conclusion The risk factor resulted in diabetic foot patients infected multiple drug -resistant bacteria is more ,and the amputation rate of patients with infection group is obviously higher than that of patients who are not infected ,to ensure that the prognosis of patients with diabetic foot level,should strengthen the control of multiple drug -resistant bacteria infection ,thus to better achieve treatment goals .
ABSTRACT
Objective To explore influences of improved intramuscular injection on quality of benzathine benzylpenicillin medication.Methods The cluster random sampling was adopted to select 178 patients who needed injection of 240U benzathine benzylpenicillin.A self-control study design was used,and benzathine benzylpenicillin was injected in both sides with each of 1 200 000 units.The left side was injected via routine method,while the right side was injected by an improved intramuscular injection.One-time success rate,degree and duration of pain during and after injection were recorded.Results The differences of one-time success rate,pain during injection,pain after injection,duration of pain after injection and incidence of induration after injection between two groups were statistically significant(P＜0.01).Conclusion The improved intramuscular injection can improve one-time success rate of benzathine benzylpenicillin,reduce pain during injection and local pain after injection,shorten duration of pain and decrease incidence of induration after injection.